113241-47-7
Chemical Structure
BRL-32872
- CAS No.: 113241-47-7
- Formula:C29H36ClN3O7
- Molecular Weight:574.07
IUPAC Name: N-(3-((3,4-dimethoxyphenethyl)(methyl)amino)propyl)-N-(3,4-dimethoxyphenyl)-4-nitrobenzamide hydrochloride
InChIKey: CMKVOHIRMCFVBJ-UHFFFAOYSA-N
SMILES: O=C(N(C1=CC=C(OC)C(OC)=C1)CCCN(CCC2=CC=C(OC)C(OC)=C2)C)C3=CC=C([N+]([O-])=O)C=C3.Cl
Biological Activity: BRL-32872 is a potent human ether-a-go-go-related gene (hERG) potassium channel blocker (IC50=241 nM in isolated cardiomyocytes; 19.8 nM in HEK293 cells). BRL-32872 is promising for research of cardiac arrhythmias (e.g., atrial/ventricular rhythms) [1].
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BRL-32872 | BRL-32872 is a potent human ether-a-go-go-related gene (hERG) potassium channel blocker (IC50=241 nM in isolated cardiomyocytes; 19.8 nM in HEK293 cells). BRL-32872 is promising for research of cardiac arrhythmias (e.g., atrial/ventricular rhythms) . | |||||||||||||||||||||
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Keywords
