117086-68-7
117086-68-7
Chemical Structure
Ricasetron
Synonym(s): BRL-46470
- CAS No.: 117086-68-7
- Formula:C19H27N3O
- Molecular Weight:313.44
IUPAC Name: 3,3-dimethyl-N-((1R,3r,5S)-8-methyl-8-azabicyclo[3.2.1]octan-3-yl)indoline-1-carboxamide
InChIKey: ILXWRFDRNAKTDD-QDMKHBRRSA-N
SMILES: O=C(N1C(C=CC=C2)=C2C(C)(C)C1)N[C@H]3C[C@@H](CC4)N(C)[C@@H]4C3
Biological Activity: Ricasetron (BRL-46470) is a selective and orally active 5-HT3 receptor antagonist. Ricasetron displays little or no affinity for a variety of other neurotransmitter receptors. Ricasetron has anxiolytic and antiemetic effects[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Ricasetron | 98.62% | Ricasetron (BRL-46470) is a selective and orally active 5-HT3 receptor antagonist. Ricasetron displays little or no affinity for a variety of other neurotransmitter receptors. Ricasetron has anxiolytic and antiemetic effects. | ||||||||||||||||||||
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References
- [1]. Steward LJ, et al. Evidence that the atypical 5-HT3 receptor ligand, [3H]-BRL46470, labels additional 5-HT3 binding sites compared to [3H]-granisetron. Br J Pharmacol. 1995 Sep;116(2):1781-8. [Content Brief]
- [2]. Gao B, et al. Effects of sub-chronic treatment with chlordiazepoxide, buspirone and the 5-HT3 receptor antagonist, BRL 46470, on the social behaviour of mice. Neuropharmacology. 1992 Mar;31(3):207-13. [Content Brief]
Keywords
