1189884-36-3
1189884-36-3
Chemical Structure
Trofosfamide-d4
- CAS No.: 1189884-36-3
- Formula:C9H14D4Cl3N2O2P
- Molecular Weight:327.61
IUPAC Name: 2-(bis(2-chloroethyl)amino)-3-(2-chloroethyl)-1,3,2-oxazaphosphinane 2-oxide-4,4,5,5-d4
InChIKey: UMKFEPPTGMDVMI-QEOHIWEKSA-N
SMILES: N(CCCl)(CCCl)P1(=O)N(CCCl)C(C(CO1)([2H])[2H])([2H])[2H]
Biological Activity: Trofosfamide-d4 is the deuterium labeled Trofosfamide. Trofosfamide is an orally bioavailable oxazaphosphorine derivative with antineoplastic activity[1][2].
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Trofosfamide-d4 | Trofosfamide-d4 is the deuterium labeled Trofosfamide. Trofosfamide is an orally bioavailable oxazaphosphorine derivative with antineoplastic activity. | |||||||||||||||||||||
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Trofosfamide | 99.66% | Trofosfamide is an orally bioavailable oxazaphosphorine derivative with antineoplastic activity. | ||||||||||||||||||||
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References
- [1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief]
- [2]. Witte HM, et al. Trofosfamide in the treatment of elderly or frail patients with diffuse large B-cell lymphoma. J Cancer Res Clin Oncol. 2019 Jan;145(1):129-136. [Content Brief]
Keywords
