120128-14-5
120128-14-5
Chemical Structure
Thrazarine
Synonym(s): FR 900840
- CAS No.: 120128-14-5
- Formula:C7H11N3O5
- Molecular Weight:217.18
IUPAC Name: O-((R)-2-diazo-3-hydroxybutanoyl)-L-serine
InChIKey: WAKGSHQRLIGGLB-DMTCNVIQSA-N
SMILES: N[C@H](C(O)=O)COC(C([C@@H](C)O)=[N+]=[N-])=O
Biological Activity: Thrazarine (FR 900840) is an oncology antibiotic that can be produced by Streptomyces coerulescens MH802-fF5. Thrazarine directly inhibits DNA synthesis and tumor cell growth. Thrazarine can specifically induce lysis of tumor cells co-cultured with non-activated macrophages. Thrazarine is used in cancer research[1].
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Thrazarine | Thrazarine (FR 900840) is an oncology antibiotic that can be produced by Streptomyces coerulescens MH802-fF5. Thrazarine directly inhibits DNA synthesis and tumor cell growth. Thrazarine can specifically induce lysis of tumor cells co-cultured with non-activated macrophages. Thrazarine is used in cancer research. | |||||||||||||||||||||
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References
Keywords
