120609-05-4
![5-[3-[(2,2,2-Trifluoroacetyl)amino]-1-propyn-1-yl]uridine Chemical Structure](http://file.medchemexpress.cn/product_pic/hy-152580.gif "5-[3-[(2,2,2-Trifluoroacetyl)amino]-1-propyn-1-yl]uridine Chemical Structure")
Chemical Structure
5-[3-[(2,2,2-Trifluoroacetyl)amino]-1-propyn-1-yl]uridine
- CAS No.: 120609-05-4
- Formula:C14H14F3N3O7
- Molecular Weight:393.27
IUPAC Name: N-(3-(1-((2R,3S,4R,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)prop-2-yn-1-yl)-2,2,2-trifluoroacetamide
InChIKey: CYFPGTPDBOIBGX-UYAYMFIHSA-N
SMILES: O[C@@H]1[C@H](O)[C@H](N2C(NC(C(C#CCNC(C(F)(F)F)=O)=C2)=O)=O)O[C@@H]1CO
Biological Activity: 5-[3-[(2,2,2-Trifluoroacetyl)amino]-1-propyn-1-yl]uridine is a thymidine analogue. Analogs of this series have insertional activity towards replicated DNA. They can be used to label cells and track DNA synthesis[1]. 5-[3-[(2,2,2-Trifluoroacetyl)amino]-1-propyn-1-yl]uridine is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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5-[3-[(2,2,2-Trifluoroacetyl)amino]-1-propyn-1-yl]uridine | 5-[3-[(2,2,2-Trifluoroacetyl)amino]-1-propyn-1-yl]uridine is a thymidine analogue. Analogs of this series have insertional activity towards replicated DNA. They can be used to label cells and track DNA synthesis. 5-[3-[(2,2,2-Trifluoroacetyl)amino]-1-propyn-1-yl]uridine is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. | |||||||||||||||||||||
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