1210803-60-3
Chemical Structure
GPR183 antagonist-4
- CAS No.: 1210803-60-3
- Formula:C19H25N3O5
- Molecular Weight:375.43
IUPAC Name: 2-(2,6-dimethyl-4-oxo-1,4-dihydropyrimidin-5-yl)-N-(1-(3,4,5-trimethoxyphenyl)ethyl)acetamide
InChIKey: FNHHPTIFDHMLHT-UHFFFAOYSA-N
SMILES: O=C1N=C(NC(=C1CC(=O)NC(C2=CC(OC)=C(OC)C(OC)=C2)C)C)C
Biological Activity: GPR183 antagonist-4 is a potent and selective GPR183 antagonist with an IC50 of 8.31 nM. GPR183 antagonist-4 inhibits receptor activation-mediated calcium signaling by antagonizing GPR183, and exhibits efficacy in ameliorating neuropathic pain-related allodynia. GPR183 antagonist-4 is useful for research on GPR183 signaling and neuropathic pain[1].
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GPR183 antagonist-4 | GPR183 antagonist-4 is a potent and selective GPR183 antagonist with an IC50 of 8.31 nM. GPR183 antagonist-4 inhibits receptor activation-mediated calcium signaling by antagonizing GPR183, and exhibits efficacy in ameliorating neuropathic pain-related allodynia. GPR183 antagonist-4 is useful for research on GPR183 signaling and neuropathic pain. | |||||||||||||||||||||
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