1213269-23-8

WZ4002 Chemical Structure
1213269-23-8

Chemical Structure

WZ4002

  • CAS No.: 1213269-23-8
  • Formula:C25H27ClN6O3
  • Molecular Weight:494.97

IUPAC Name: N-(3-((5-chloro-2-((2-methoxy-4-(4-methylpiperazin-1-yl)phenyl)amino)pyrimidin-4-yl)oxy)phenyl)acrylamide

InChIKey: ITTRLTNMFYIYPA-UHFFFAOYSA-N

SMILES: COC1=C(C=CC(N2CCN(CC2)C)=C1)NC3=NC=C(C(OC4=CC(NC(C=C)=O)=CC=C4)=N3)Cl

Biological Activity: WZ4002 is a mutant selective EGFR inhibitor with IC50s of 2, 8, 3 and 2 nM for EGFRL858R, EGFRL858R/T790M, EGFRE746_A750 and EGFRE746_A750/T790M, respectively.

Cat. No. Product Name Purity Description Pricing
HY-12026 		WZ4002 98.99% WZ4002 is a mutant selective EGFR inhibitor with IC50s of 2, 8, 3 and 2 nM for EGFRL858R, EGFRL858R/T790M, EGFRE746_A750 and EGFRE746_A750/T790M, respectively.
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