122981-77-5
Chemical Structure
(Rac)-Chem-0199
- CAS No.: 122981-77-5
- Formula:C13H18N2O2
- Molecular Weight:234.29
InChIKey: SQIPUOGHUWXIRH-UHFFFAOYSA-N
SMILES: CC1(C)N(O)C(C2=CC=CC=C2)[N+]([O-])=C1CC
Biological Activity: (Rac)-Chem-0199 is the racemic mixture of Chem-0199 (HY-178193). Chem-0199 is an Adipocyte Enhancer-Binding Protein 1 (AEBP1) inhibitor. Chem-0199 can disrupt the interaction between AEBP1 and CKAP4, thereby enhances antitumor immunity. Chem-0199 can inhibit Akt phosphorylation (p-Akt) and downregulates PD-L1 expression. Chem-0199 can be used for the research of cancer, such as colon cancer[1].
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(Rac)-Chem-0199 | 99.81% | (Rac)-Chem-0199 is the racemic mixture of Chem-0199 (HY-178193). Chem-0199 is an Adipocyte Enhancer-Binding Protein 1 (AEBP1) inhibitor. Chem-0199 can disrupt the interaction between AEBP1 and CKAP4, thereby enhances antitumor immunity. Chem-0199 can inhibit Akt phosphorylation (p-Akt) and downregulates PD-L1 expression. Chem-0199 can be used for the research of cancer, such as colon cancer. | ||||||||||||||||||||
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Keywords