1260431-28-4
Chemical Structure
Cryptophycin analog 1
- CAS No.: 1260431-28-4
- Formula:C37H48ClN3O8
- Molecular Weight:698.25
IUPAC Name: (3S,10R,16S,E)-16-((S)-1-((2R,3R)-3-(4-(aminomethyl)phenyl)oxiran-2-yl)ethyl)-10-(3-chloro-4-methoxybenzyl)-3-isobutyl-6,6-dimethyl-1,4-dioxa-8,11-diazacyclohexadec-13-ene-2,5,9,12-tetraone
InChIKey: VGYCIPORVJQZDT-YXCXXXRFSA-N
SMILES: O=C(NCC(C)(C)C(O[C@H](C(O1)=O)CC(C)C)=O)[C@@H](CC2=CC=C(OC)C(Cl)=C2)NC(/C=C/C[C@H]1[C@H](C)[C@@H]3[C@H](O3)C4=CC=C(CN)C=C4)=O
Biological Activity: Cryptophycin analog 1 is an ADC payload. Cryptophycin analog 1 shows anticancer activity. Cryptophycin analog 1 displays cell activity an order of magnitude more potent than approved ADC payloads MMAE and DM1[1].
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Cryptophycin analog 1 | Cryptophycin analog 1 is an ADC payload. Cryptophycin analog 1 shows anticancer activity. Cryptophycin analog 1 displays cell activity an order of magnitude more potent than approved ADC payloads MMAE and DM1. | |||||||||||||||||||||
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Keywords
