126502-12-3
126502-12-3
Chemical Structure
2’-Fluoro-2’-deoxy-N6-methylarabinoadenosine
- CAS No.: 126502-12-3
- Formula:C11H14FN5O3
- Molecular Weight:283.26
IUPAC Name: (2R,3R,4S,5R)-4-fluoro-2-(hydroxymethyl)-5-(6-(methylamino)-9H-purin-9-yl)tetrahydrofuran-3-ol
InChIKey: XVGMWRQRNLVRLF-WCGPTHBMSA-N
SMILES: O[C@H]1[C@H](F)[C@H](N2C(N=CN=C3NC)=C3N=C2)O[C@@H]1CO
Biological Activity: 2’-Fluoro-2’-deoxy-N6-methylarabinoadenosine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
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2’-Fluoro-2’-deoxy-N6-methylarabinoadenosine | 2’-Fluoro-2’-deoxy-N6-methylarabinoadenosine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc. | |||||||||||||||||||||
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References
