1276483-10-3
1276483-10-3
Chemical Structure
(rac)-Viloxazine-d5 hydrochloride
- CAS No.: 1276483-10-3
- Formula:C13H15D5ClNO3
- Molecular Weight:278.79
IUPAC Name: 2-((2-(ethoxy-d5)phenoxy)methyl)morpholine hydrochloride
InChIKey: HJOCKFVCMLCPTP-LUIAAVAXSA-N
SMILES: O(CC1CNCCO1)C2=C(OC(C([2H])([2H])[2H])([2H])[2H])C=CC=C2.Cl
Biological Activity: (rac)-Viloxazine-d5 (hydrochloride) is the deuterium labeled (rac)-Viloxazine hydrochloride[1].
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(rac)-Viloxazine-d5 hydrochloride | (rac)-Viloxazine-d5 (hydrochloride) is the deuterium labeled (rac)-Viloxazine hydrochloride. | |||||||||||||||||||||
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Viloxazine hydrochloride | 98.94% | Viloxazine hydrochloride is a non-brain-penetrant, selective norepinephrine transporter (NET) inhibitor (IC50=0.26 μM) and 5-HT receptor modulator. Viloxazine antagonizes 5-HT2B receptors (Ki=4.2 μM) and agonizes 5-HT2C receptors (EC50=32 μM), respectively, and enhances 5-HT neurotransmission by modulating 5-HT2B/C receptors. Viloxazine also competitively inhibits NET from increasing NE and DA levels in the synaptic cleft, and can be used in the study of attention deficit hyperactivity disorder (ADHD). | ||||||||||||||||||||
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References
