1287303-66-5
Chemical Structure
TP-1161
- CAS No.: 1287303-66-5
- Formula:C50H47N15O13S3
- Molecular Weight:1162.20
IUPAC Name: (12Z,32Z,102Z,142Z,182Z,6S,9E,17S)-9-ethylidene-6-((R)-1-hydroxyethyl)-105,17-dimethyl-21,24-dimethylene-4,7,11,15,19,22-hexaoxo-N-(3-oxo-3-((3-oxo-3-((2-oxopropyl)amino)prop-1-en-2-yl)amino)prop-1-en-2-yl)-5,8,12,16,20,23-hexaaza-1(4,2),10(2,4)-dioxazola-3,14,18(2,4)-trithiazola-2(2,3)-pyridinacyclotetracosaphane-26-carboxamide
InChIKey: YGUKQAWJFUHKHO-SLBZEGPGSA-N
SMILES: CC(CNC(C(NC(C(NC(C1=CC=C(C2=NC(C(N[C@@](C(N/C(C3=NC(C(NCC4=NC(C(N[C@H](C5=NC(C(NC(C(NC(C6=NC7=CO6)=C)=O)=C)=O)=CS5)C)=O)=CS4)=O)=C(O3)C)=C/C)=O)([H])[C@H](O)C)=O)=CS2)C7=N1)=O)=C)=O)=C)=O)=O
Biological Activity: TP-1161 is a novel thiopeptide antibiotic. TP-1161 has strong inhibitory effects on various Gram positive bacteria (MIC = 0.25-4 μg/mL), but is inactive against Gram negative bacteria. TP-1161 can be used for research on bacterial infections[1].
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TP-1161 | TP-1161 is a novel thiopeptide antibiotic. TP-1161 has strong inhibitory effects on various Gram positive bacteria (MIC = 0.25-4 μg/mL), but is inactive against Gram negative bacteria. TP-1161 can be used for research on bacterial infections. | |||||||||||||||||||||
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Keywords
