1314206-29-5
Chemical Structure
RU-505
- CAS No.: 1314206-29-5
- Formula:C28H32FN5O
- Molecular Weight:473.58
IUPAC Name: N-benzyl-2-(tert-butyl)-N-(2-(dimethylamino)ethyl)-7-(4-fluorophenyl)pyrazolo[1,5-a]pyrimidine-5-carboxamide
InChIKey: GMFHHCFJJZWFBW-UHFFFAOYSA-N
SMILES: O=C(C1=NC2=CC(C(C)(C)C)=NN2C(C3=CC=C(F)C=C3)=C1)N(CCN(C)C)CC4=CC=CC=C4
Biological Activity: RU-505 is an effective β-amyloid (Aβ)-fibrinogen interaction inhibitor with IC50s of 5.00 and 2.72 μM in fluorescence polarization (FP) and AlphaLISA assays, respectively. RU-505 is highly permeable to the BBB. RU-505 reduces cerebral amyloid angiopathy (CAA). RU-505 can be used for the research of Alzheimer’s disease (AD)[1].
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RU-505 | RU-505 is an effective β-amyloid (Aβ)-fibrinogen interaction inhibitor with IC50s of 5.00 and 2.72 μM in fluorescence polarization (FP) and AlphaLISA assays, respectively. RU-505 is highly permeable to the BBB. RU-505 reduces cerebral amyloid angiopathy (CAA). RU-505 can be used for the research of Alzheimer’s disease (AD). | |||||||||||||||||||||
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Keywords
