1336960-13-4
1336960-13-4
Chemical Structure
GSK2193874
- CAS 番号: 1336960-13-4
- Formula:C37H38BrF3N4O
- Molecular Weight:691.62
IUPAC Name: 3-([1,4'-bipiperidin]-1'-ylmethyl)-7-bromo-N-(1-phenylcyclopropyl)-2-(3-(trifluoromethyl)phenyl)quinoline-4-carboxamide
InChIKey: UIVOZBSCHXCGPS-UHFFFAOYSA-N
SMILES: O=C(C1=C(CN2CCC(N3CCCCC3)CC2)C(C4=CC=CC(C(F)(F)F)=C4)=NC5=CC(Br)=CC=C15)NC6(C7=CC=CC=C7)CC6
Biological Activity: GSK2193874 is an orally active, potent, and selective TRPV4 antagonist with IC50s of 2 nM and 40 nM for rTRPV4 and hTRPV4[1].
| 製品番号 | 製品名 | 純度 | 製品説明 | Pricing | |||||||||||||||||||
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GSK2193874 | 99.91% | GSK2193874 is an orally active, potent, and selective TRPV4 antagonist with IC50s of 2 nM and 40 nM for rTRPV4 and hTRPV4. | ||||||||||||||||||||
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GSK2193874 (Standard) | ≥98% | GSK2193874 (Standard) is the analytical standard of GSK2193874 (HY-100720). This product is intended for research and analytical applications. GSK2193874 is an orally active, potent, and selective TRPV4 antagonist with IC50s of 2 nM and 40 nM for rTRPV4 and hTRPV4. | ||||||||||||||||||||
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References
Keywords
