1337920-46-3
Chemical Structure
RO5488608
- CAS No.: 1337920-46-3
- Formula:C23H17F3N2O4S
- Molecular Weight:474.45
IUPAC Name: 3'-(7-methyl-2-oxo-8-(trifluoromethyl)-2,3-dihydro-1H-benzo[b][1,4]diazepin-4-yl)-[1,1'-biphenyl]-3-sulfonic acid
InChIKey: FQNZBSFUVZKONP-UHFFFAOYSA-N
SMILES: O=C1NC2=C(N=C(C1)C3=CC=CC(C4=CC=CC(S(=O)(O)=O)=C4)=C3)C=C(C)C(C(F)(F)F)=C2
Biological Activity: RO5488608 is a negative allosteric metabotropic modulator of glutamate receptor 2/3. RO5488608 inhibits LY354740 (HY-18941)-induced intracellular Ca2+ release and can be used for study of antidepressant[1].
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RO5488608 | RO5488608 is a negative allosteric metabotropic modulator of glutamate receptor 2/3. RO5488608 inhibits LY354740 (HY-18941)-induced intracellular Ca2+ release and can be used for study of antidepressant. | |||||||||||||||||||||
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Keywords