134085-79-3
Chemical Structure
Zaltoprofen sulfoxide
- CAS No.: 134085-79-3
- Formula:C17H14O4S
- Molecular Weight:314.36
InChIKey: BMXFBJRSBWVAIU-UHFFFAOYSA-N
SMILES: O=C(C(C)C1=CC=C2C(CC(C3=C(S2=O)C=CC=C3)=O)=C1)O
Biological Activity: Zaltoprofen sulfoxide (Compound M2) is the main metabolite of Zaltoprofen (HY-B0619). Zaltoprofen sulfoxide is an efficient and selective COX-2 inhibitor (IC50 = 45.38 nM) and a PPAR-γ activator. Zaltoprofen sulfoxide effectively inhibits NF-κB and MAPK inflammatory signaling pathways and alleviates acute lung injury induced by LPS (HY-D1056B3). Zaltoprofen sulfoxide can be used for the study of acute lung injury[1].
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Zaltoprofen sulfoxide | Zaltoprofen sulfoxide (Compound M2) is the main metabolite of Zaltoprofen (HY-B0619). Zaltoprofen sulfoxide is an efficient and selective COX-2 inhibitor (IC50 = 45.38 nM) and a PPAR-γ activator. Zaltoprofen sulfoxide effectively inhibits NF-κB and MAPK inflammatory signaling pathways and alleviates acute lung injury induced by LPS (HY-D1056B3). Zaltoprofen sulfoxide can be used for the study of acute lung injury. | |||||||||||||||||||||
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Keywords
