Zaltoprofen sulfoxide
Zaltoprofen sulfoxide (Compound M2) is the main metabolite of Zaltoprofen (HY-B0619). Zaltoprofen sulfoxide is an efficient and selective COX-2 inhibitor (IC50 = 45.38 nM) and a PPAR-γ activator. Zaltoprofen sulfoxide effectively inhibits NF-κB and MAPK inflammatory signaling pathways and alleviates acute lung injury induced by LPS (HY-D1056B3). Zaltoprofen sulfoxide can be used for the study of acute lung injury.
For research use only. We do not sell to patients.
- CAS No.: 134085-79-3
- Formula: C17H14O4S
- Molecular Weight:314.36
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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COX-2 45.38 nM (IC50) |
PPAR-γ |
Chemical Information
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CAS No. 134085-79-3
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Molecular Weight 314.36
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Formula C17H14O4S
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SMILES
O=C(C(C)C1=CC=C2C(CC(C3=C(S2=O)C=CC=C3)=O)=C1)O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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