134179-44-5
Chemical Structure
Phthalamide-PEG3-azide
- CAS No.: 134179-44-5
- Formula:C16H20N4O5
- Molecular Weight:348.35
IUPAC Name: 2-(2-(2-(2-(2-azidoethoxy)ethoxy)ethoxy)ethyl)isoindoline-1,3-dione
InChIKey: BEELPXILEIOFRO-UHFFFAOYSA-N
SMILES: O=C1N(CCOCCOCCOCCN=[N+]=[N-])C(C2=C1C=CC=C2)=O
Biological Activity: Phthalamide-PEG3-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Phthalamide-PEG3-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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Phthalamide-PEG3-azide | Phthalamide-PEG3-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. Phthalamide-PEG3-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups. | |||||||||||||||||||||
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Keywords
