1359358-36-3
1359358-36-3
Chemical Structure
E0714
- CAS No.: 1359358-36-3
- Formula:C20H17N3O3
- Molecular Weight:347.37
InChIKey: BYKXYKHJOXLTQW-UHFFFAOYSA-N
SMILES: CNC(C1=CC=CN(C1=O)C2=CC=C(C=C2)NC(C3=CC=CC=C3)=O)=O
Biological Activity: E0714 is a blood-brain barrier-permeable, selective Kv7.2 potassium channel activator, with EC50 values of 1.90 μM and 0.021 μM for homotetrameric Kv7.2 channels and heterotetrameric Kv7.2/7.3 channels, respectively. E0714 exhibits anticonvulsant activity. E0714 can be used in research related to epilepsy[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
E0714 | E0714 is a blood-brain barrier-permeable, selective Kv7.2 potassium channel activator, with EC50 values of 1.90 μM and 0.021 μM for homotetrameric Kv7.2 channels and heterotetrameric Kv7.2/7.3 channels, respectively. E0714 exhibits anticonvulsant activity. E0714 can be used in research related to epilepsy. | |||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
References
Keywords
