1370037-59-4
Chemical Structure
ST09
- CAS No.: 1370037-59-4
- Formula:C24H32ClN3O2S
- Molecular Weight:462.05
IUPAC Name: S-(3-((6-((6-chloro-1,2,3,4-tetrahydroacridin-9-yl)amino)hexyl)amino)-3-oxopropyl) ethanethioate
InChIKey: DBUIIUVPFUGTNS-UHFFFAOYSA-N
SMILES: CC(SCCC(NCCCCCCNC1=C(C=CC(Cl)=C2)C2=NC3=C1CCCC3)=O)=O
Biological Activity: ST09 is an efficient and low toxicity Curcumin (HY-N0005) derivative. ST09 significantly inhibits cell migration and downregulates the expression of MMP1, MMP2, and Vimentin. ST09 has strong cytotoxicity to breast cancer cells, such as MDA-MB-231, MCF7 and T47D cells. ST09 induces cell apoptosis by upregulating Bax and cleaved caspase-3/9. ST09 can be used in the research of cancer such as breast cancer[1].
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ST09 | ST09 is an efficient and low toxicity Curcumin (HY-N0005) derivative. ST09 significantly inhibits cell migration and downregulates the expression of MMP1, MMP2, and Vimentin. ST09 has strong cytotoxicity to breast cancer cells, such as MDA-MB-231, MCF7 and T47D cells. ST09 induces cell apoptosis by upregulating Bax and cleaved caspase-3/9. ST09 can be used in the research of cancer such as breast cancer. | |||||||||||||||||||||
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Keywords
