137076-54-1
137076-54-1
Chemical Structure
DOTA-tri(t-butyl ester)
- CAS No.: 137076-54-1
- Formula:C28H52N4O8
- Molecular Weight:572.73
IUPAC Name: 2-(4,7,10-tris(2-(tert-butoxy)-2-oxoethyl)-1,4,7,10-tetraazacyclododecan-1-yl)acetic acid
InChIKey: RVUXZXMKYMSWOM-UHFFFAOYSA-N
SMILES: CC(C)(OC(CN1CCN(CC(O)=O)CCN(CC(OC(C)(C)C)=O)CCN(CC(OC(C)(C)C)=O)CC1)=O)C
Biological Activity: DOTA-tri(t-butyl ester) belongs to the DOTA class of chelating agents. DOTA-tri(t-butyl ester) is a key raw material for synthesizing nanospherical magnetic resonance imaging (MRI) contrast agents, which are used in MR angiography and tumor angiogenesis imaging[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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DOTA-tri(t-butyl ester) | 99.09% | DOTA-tri(t-butyl ester) belongs to the DOTA class of chelating agents. DOTA-tri(t-butyl ester) is a key raw material for synthesizing nanospherical magnetic resonance imaging (MRI) contrast agents, which are used in MR angiography and tumor angiogenesis imaging. | ||||||||||||||||||||
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References
- [1]. Kaneshiro TL, et, al. Synthesis and evaluation of globular Gd-DOTA-monoamide conjugates with precisely controlled nanosizes for magnetic resonance angiography. Biomacromolecules. 2008 Oct;9(10):2742-8. [Content Brief]
- [2]. Sosabowski JK, et al. Conjugation of DOTA-like chelating agents to peptides and radiolabeling with trivalent metallic isotopes. Nat Protoc. 2006;1(2):972-6. [Content Brief]
Keywords
