138199-64-1
Chemical Structure
MK-852
Synonym(s): L-367073
- CAS No.: 138199-64-1
- Formula:C34H47N9O12S3
- Molecular Weight:869.99
IUPAC Name: (6S,9R,14R,17S,23S,25aR)-9-acetamido-6-(2-amino-2-oxoethyl)-23-(4-(aminomethyl)benzyl)-17-(carboxymethyl)-1,1-dimethyl-5,8,16,19,22,25-hexaoxoicosahydro-1H,3H-thiazolo[4,3-p][1,2]dithia[5,8,11,14,17,20]hexaazacyclotricosine-14-carboxylic acid
InChIKey: IHTQUFFCUYSOIH-SBTHHMAGSA-N
SMILES: O=C1N2[C@](C(C)(SC2)C)([H])C(N[C@H](C(NCC(N[C@H](C(N[C@@H](CSSC[C@@H](C(N[C@H]1CC(N)=O)=O)NC(C)=O)C(O)=O)=O)CC(O)=O)=O)=O)CC3=CC=C(C=C3)CN)=O
Biological Activity: MK-852 (L-367073) is an effective GPIIb/IIIa receptor antagonist. MK-852 can significantly inhibit the binding of fibrinogen to platelets in vitro. MK-852can be used for the study of thrombosis[1].
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MK-852 | MK-852 (L-367073) is an effective GPIIb/IIIa receptor antagonist. MK-852 can significantly inhibit the binding of fibrinogen to platelets in vitro. MK-852can be used for the study of thrombosis. | |||||||||||||||||||||
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