1386915-48-5
1386915-48-5
Chemical Structure
Ambrisentan sodium
Synonym(s): BSF 208075 sodium; LU 208075 sodium
- CAS No.: 1386915-48-5
- Formula:C22H21N2NaO4
- Molecular Weight:400.40
IUPAC Name: sodium (S)-2-((4,6-dimethylpyrimidin-2-yl)oxy)-3-methoxy-3,3-diphenylpropanoate
InChIKey: GNDMILPGCDIGHE-FSRHSHDFSA-M
SMILES: O=C(O[Na])[C@@H](OC1=NC(C)=CC(C)=N1)C(C2=CC=CC=C2)(OC)C3=CC=CC=C3
Biological Activity: Ambrisentan (BSF 208075) sodium is a selective and orally active ET type A receptor (ETAR) antagonist[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
Ambrisentan sodium | Ambrisentan (BSF 208075) sodium is a selective and orally active ET type A receptor (ETAR) antagonist. | |||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
References
- [1]. Okamoto T, et al. Antifibrotic effects of Ambrisentan, an endothelin-A receptor antagonist, in a non-alcoholic steatohepatitis mouse model. World J Hepatol. 2016 Aug 8;8(22):933-41. [Content Brief]
- [2]. Lisk C, et al. Nrf2 activation: a potential strategy for the prevention of acute mountain sickness. Free Radic Biol Med. 2013 Oct;63:264-73. [Content Brief]
Keywords
