139145-84-9
Chemical Structure
Parogrelil hydrochloride
Synonym(s): NM-702; NT-702
- CAS No.: 139145-84-9
- Formula:C19H19BrCl2N4O2
- Molecular Weight:486.19
IUPAC Name: 4-bromo-6-(3-(4-chlorophenyl)propoxy)-5-((pyridin-3-ylmethyl)amino)pyridazin-3(2H)-one hydrochloride
InChIKey: QWGUGDYWUADMGB-UHFFFAOYSA-N
SMILES: O=C1C(Br)=C(NCC2=CC=CN=C2)C(OCCCC3=CC=C(Cl)C=C3)=NN1.Cl
Biological Activity: Parogrelil (hydrochloride) (NM-702) is a phosphodiesterase inhibitor with activity in inhibiting intermittent claudication. Parogrelil (hydrochloride) selectively inhibits PDE3, inhibits human platelet aggregation in vitro and rat aortic contraction, and improves walking distance and plantar surface temperature in the rat femoral artery ligation model, with better effects than cilostazol.
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Parogrelil hydrochloride | Parogrelil (hydrochloride) (NM-702) is a phosphodiesterase inhibitor with activity in inhibiting intermittent claudication. Parogrelil (hydrochloride) selectively inhibits PDE3, inhibits human platelet aggregation in vitro and rat aortic contraction, and improves walking distance and plantar surface temperature in the rat femoral artery ligation model, with better effects than cilostazol. | |||||||||||||||||||||
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Keywords
