1392421-71-4
1392421-71-4
Chemical Structure
PI3K/mTOR Inhibitor-9
- CAS No.: 1392421-71-4
- Formula:C23H27N7O2
- Molecular Weight:433.51
IUPAC Name: (R)-4-(8-(1H-indol-4-yl)-2-((S)-3-methylmorpholino)-7H-purin-6-yl)-3-methylmorpholine
InChIKey: BYPBFDASESWSQG-CABCVRRESA-N
SMILES: C[C@H]1N(CCOC1)C2=C3C(N=C(C4=C5C(NC=C5)=CC=C4)N3)=NC(N6[C@H](COCC6)C)=N2
Biological Activity: PI3K/mTOR Inhibitor-9 (Compound 1) is a potent mTOR and PI3K inhibitor with IC50 values of 38 nM, 6.6 μM, 6.6 μM and 0.8 μM against mTOR (phospho-S6 cellular assay), PI3Kα, PI3Kγ and PI3Kδ, respectively[1].
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PI3K/mTOR Inhibitor-9 | PI3K/mTOR Inhibitor-9 (Compound 1) is a potent mTOR and PI3K inhibitor with IC50 values of 38 nM, 6.6 μM, 6.6 μM and 0.8 μM against mTOR (phospho-S6 cellular assay), PI3Kα, PI3Kγ and PI3Kδ, respectively. | |||||||||||||||||||||
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References
Keywords
