139755-95-6
139755-95-6
Chemical Structure
Pyrazole N-Desmethyl sildenafil
- CAS No.: 139755-95-6
- Formula:C21H28N6O4S
- Molecular Weight:460.55
InChIKey: ZLJVUHMTFSCAGQ-UHFFFAOYSA-N
SMILES: O=C1N=C(C2=C(OCC)C=CC(S(=O)(N3CCN(CC3)C)=O)=C2)NC4=C1NN=C4CCC
Biological Activity: Pyrazole N-Desmethyl sildenafil (Compound 10) is an analog of Sildenafil (HY-15025). Pyrazole N-Desmethyl sildenafil shows 16% inhibition on Trypanosoma brucei phosphodiesterase B1 (TbrPDEB1) with 100 µM[1].
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Pyrazole N-Desmethyl sildenafil | Pyrazole N-Desmethyl sildenafil (Compound 10) is an analog of Sildenafil (HY-15025). Pyrazole N-Desmethyl sildenafil shows 16% inhibition on Trypanosoma brucei phosphodiesterase B1 (TbrPDEB1) with 100 µM. | |||||||||||||||||||||
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Pyrazole N-Demethyl Sildenafil-d3 | Pyrazole N-Demethyl Sildenafil-d3 is the deuterium labeled Pyrazole N-Demethyl Sildenafil. | |||||||||||||||||||||
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References
