1403764-72-6
1403764-72-6
Chemical Structure
PFI-1
- CAS No.: 1403764-72-6
- Formula:C16H17N3O4S
- Molecular Weight:347.39
IUPAC Name: 2-methoxy-N-(3-methyl-2-oxo-1,2,3,4-tetrahydroquinazolin-6-yl)benzenesulfonamide
InChIKey: TXZPMHLMPKIUGK-UHFFFAOYSA-N
SMILES: O=S(C1=CC=CC=C1OC)(NC2=CC3=C(NC(N(C)C3)=O)C=C2)=O
Biological Activity: PFI-1, a chemical probe, is a selective BET (bromodomain-containing protein) inhibitor for BRD4 with IC50 of 0.22 μM in a cell-free assay.
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PFI-1 | 99.87% | PFI-1, a chemical probe, is a selective BET (bromodomain-containing protein) inhibitor for BRD4 with IC50 of 0.22 μM in a cell-free assay. | ||||||||||||||||||||
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Keywords
