1415264-56-0
Chemical Structure
Virodhamine TFA
- CAS No.: 1415264-56-0
- Formula:C24H38F3NO4
- Molecular Weight:461.56
IUPAC Name: 2-aminoethyl (5Z,8Z,11Z,14Z)-icosa-5,8,11,14-tetraenoate 2,2,2-trifluoroacetate
InChIKey: APQWCQIPZHJFAU-XVSDJDOKSA-N
SMILES: CCCCC/C=C\C/C=C\C/C=C\C/C=C\CCCC(OCCN)=O.OC(C(F)(F)F)=O
Biological Activity: Virodhamine TFA is an endocannabinoid, it regulates neurotransmission by activating the cannabinoid (CB) receptors. Virodhamine is an antagonist of CB1 receptor and an agonist of CB2 receptor. Virodhamine TFA induces megakaryocytic differentiation by triggering MAPK signaling and ROS production. Virodhamine TFA can be used for the research of various neurological disorders such as Alzheimer's and Parkinson's diseases[1][2].
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Virodhamine TFA | Virodhamine TFA is an endocannabinoid, it regulates neurotransmission by activating the cannabinoid (CB) receptors. Virodhamine is an antagonist of CB1 receptor and an agonist of CB2 receptor. Virodhamine TFA induces megakaryocytic differentiation by triggering MAPK signaling and ROS production. Virodhamine TFA can be used for the research of various neurological disorders such as Alzheimer's and Parkinson's diseases. | |||||||||||||||||||||
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- [1]. Sharma DS, et al. Virodhamine, an endocannabinoid, induces megakaryocyte differentiation by regulating MAPK activity and function of mitochondria. J Cell Physiol. 2021 Feb;236(2):1445-1453. [Content Brief]
- [2]. Hayase T. Working memory- and anxiety-related behavioral effects of repeated nicotine as a stressor: the role of cannabinoid receptors. BMC Neurosci. 2013 Feb 9;14:20. [Content Brief]
Keywords
