142103-12-6
Chemical Structure
5-Me-3’-dU-2’-phosphoramidite
- CAS No.: 142103-12-6
- Formula:C40H49N4O8P
- Molecular Weight:744.81
IUPAC Name: (2R,3R,5S)-5-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-2-(5-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite
InChIKey: GYSQEEMWSGWZLC-SXIXUTRBSA-N
SMILES: O=C(C(C)=C1)NC(N1[C@@H]2O[C@H](COC(C3=CC=CC=C3)(C4=CC=C(OC)C=C4)C5=CC=C(OC)C=C5)C[C@H]2OP(OCCC#N)N(C(C)C)C(C)C)=O
Biological Activity: 5-Me-3’-dU-2’-phosphoramidite is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
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5-Me-3’-dU-2’-phosphoramidite | 5-Me-3’-dU-2’-phosphoramidite is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc. | |||||||||||||||||||||
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Keywords
