143656-18-2
143656-18-2
Chemical Structure
Prostaglandin F2α alcohol methyl ether
- CAS No.: 143656-18-2
- Formula:C21H38O4
- Molecular Weight:354.52
IUPAC Name: (1S,3R,4R,5R)-4-((S,E)-3-hydroxyoct-1-en-1-yl)-5-((Z)-7-methoxyhept-2-en-1-yl)cyclopentane-1,3-diol
InChIKey: VWEVSUSNDAHANL-GPPPFWBLSA-N
SMILES: COCCCC/C=C\C[C@@H]1[C@H]([C@@H](C[C@@H]1O)O)/C=C/[C@@H](O)CCCCC
Biological Activity: Prostaglandin F2α alcohol methyl ether is an alcohol methyl ether G protein-coupled receptor. Prostaglandin F2α is also a luteinizing hormone in sheep and may be a nociceptive mediator in the spinal cord[1][2][3].
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Prostaglandin F2α alcohol methyl ether | Prostaglandin F2α alcohol methyl ether is an alcohol methyl ether G protein-coupled receptor. Prostaglandin F2α is also a luteinizing hormone in sheep and may be a nociceptive mediator in the spinal cord. | |||||||||||||||||||||
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References
- [1]. Richie-Jannetta R, et al. Structural determinants for calcium mobilization by prostaglandin E2 and prostaglandin F2alpha glyceryl esters in RAW 264.7 cells and H1819 cells. Prostaglandins Other Lipid Mediat. 2010 Jun;92(1-4):19-24. [Content Brief]
- [2]. Woodward DF, et al. Recent progress in prostaglandin F2α ethanolamide (prostamide F2α) research and therapeutics. Pharmacol Rev. 2013 Jul 26;65(4):1135-47. [Content Brief]
- [3]. McCracken J A, et al. Prostaglandin F2α identified as a luteolytic hormone in sheep[J]. Nature New Biology, 1972, 238(83): 129-134.
