1439095-16-5
1439095-16-5
Chemical Structure
VU0463841
- CAS No.: 1439095-16-5
- Formula:C13H8ClFN4O
- Molecular Weight:290.68
IUPAC Name: 1-(5-chloropyridin-2-yl)-3-(3-cyano-5-fluorophenyl)urea
InChIKey: KDANLHLWAYNCMV-UHFFFAOYSA-N
SMILES: O=C(NC1=NC=C(C=C1)Cl)NC2=CC(F)=CC(C#N)=C2
Biological Activity: VU0463841 is a potent, selective and brain-penetrant mGlu5 negative allosteric modulator (NAM) with an IC50 of 13 nM. VU0463841 is ineffective against mGlu1-4 and mGlu7-8. VU0463841 has the potential for the Cocaine addiction research[1].
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VU0463841 | VU0463841 is a potent, selective and brain-penetrant mGlu5 negative allosteric modulator (NAM) with an IC50 of 13 nM. VU0463841 is ineffective against mGlu1-4 and mGlu7-8. VU0463841 has the potential for the Cocaine addiction research. | |||||||||||||||||||||
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References
Keywords
