1440532-32-0
Chemical Structure
TWIK-1/TREK-1-IN-2
- CAS No.: 1440532-32-0
- Formula:C20H29F3N2O2
- Molecular Weight:386.45
InChIKey: FLNQXCGNEOXSSQ-SFHVURJKSA-N
SMILES: O[C@H](COC1=CC=C(C(F)(F)F)C=C1)CN(CC2)CCC2N3CCCCC3
Biological Activity: TWIK-1/TREK-1-IN-2 (Compound 2g) is a TWIK-1/TREK-1 inhibitor. TWIK-1/TREK-1-IN-2 inhibits TREK-1 homodimer and TWIK-1/TREK-1 heterodimer with IC50s of 10.13 μM and 15.5 μM. TWIK-1/TREK-1-IN-2 is an antidepressant[1].
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TWIK-1/TREK-1-IN-2 | TWIK-1/TREK-1-IN-2 (Compound 2g) is a TWIK-1/TREK-1 inhibitor. TWIK-1/TREK-1-IN-2 inhibits TREK-1 homodimer and TWIK-1/TREK-1 heterodimer with IC50s of 10.13 μM and 15.5 μM. TWIK-1/TREK-1-IN-2 is an antidepressant. | |||||||||||||||||||||
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Keywords