150646-45-0
Chemical Structure
(D-Phe12,Nle21,38,α-Me-Leu37)-CRF (12-41) (human, rat)
- CAS No.: 150646-45-0
- Formula:C159H267N49O43
- Molecular Weight:3553.12
SMILES: CC[C@H](C)[C@@H](C(N)=O)NC([C@H]([C@@H](C)CC)NC([C@H](CCC(O)=O)NC([C@H](CCCC)NC([C@@](CC(C)C)(C)NC([C@H](CCCCN)NC([C@H](CCCNC(N)=N)NC([C@H](CC(N)=O)NC([C@H](CO)NC([C@H](CC1=CN=CN1)NC([C@H](C)NC([C@H](CCC(N)=O)NC([C@H](CCC(N)=O)NC([C@H](C)NC([C@H](CC(C)C)NC([C@H](CCC(N)=O)NC([C@H](CCC(O)=O)NC([C@H](C)NC([C@H](CCCNC(N)=N)NC([C@H](C)NC([C@H](CCCC)NC([C@H](CCC(O)=O)NC([C@H](CC(C)C)NC([C@H](C(C)C)NC([C@H](CCC(O)=O)NC([C@H](CCCNC(N)=N)NC([C@H](CC(C)C)NC([C@H](CC(C)C)NC([C@@H](NC([C@H](N)CC2=CC=CC=C2)=O)CC3=CN=CN3)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O
Biological Activity: (D-Phe12,Nle21,38,α-Me-Leu37)-CRF (12-41) (human, rat) is a CRF antagonist. (D-Phe12,Nle21,38,α-Me-Leu37)-CRF (12-41) (human, rat) prevents the IL-1a induced Luteinizing hormone (LH) inhibition[1].
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(D-Phe12,Nle21,38,α-Me-Leu37)-CRF (12-41) (human, rat) | (D-Phe12,Nle21,38,α-Me-Leu37)-CRF (12-41) (human, rat) is a CRF antagonist. (D-Phe12,Nle21,38,α-Me-Leu37)-CRF (12-41) (human, rat) prevents the IL-1a induced Luteinizing hormone (LH) inhibition. | |||||||||||||||||||||
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