1513828-41-5
Chemical Structure
INU-101
- CAS No.: 1513828-41-5
- Formula:C21H28FN3O4S
- Molecular Weight:437.53
IUPAC Name: (1s,3R,5S,7s)-4-(2-((2-fluorophenyl)sulfonamido)-2-methylpropanamido)adamantane-1-carboxamide
InChIKey: UBAPBKDXKUTATP-OIPPAIBTSA-N
SMILES: NC([C@]12C[C@@H](C3)C(NC(C(C)(C)NS(=O)(C4=C(C=CC=C4)F)=O)=O)[C@@H](C[C@@H]3C2)C1)=O
Biological Activity: INU-101 is a potent, selective and orally active 11β-hydroxysteroid dehydrogenase (11β-HSD) type 1 inhibitor. INU-101 has highly potent inhibitory activity in mouse, monkey and human 11β-HSD1, derived from liver microsomes. INU-101 can enhance insulin sensitivity and lower the fasting blood glucose level. INU-101 can be used for the research of metabolic disease, such as diabetes[1].
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INU-101 | INU-101 is a potent, selective and orally active 11β-hydroxysteroid dehydrogenase (11β-HSD) type 1 inhibitor. INU-101 has highly potent inhibitory activity in mouse, monkey and human 11β-HSD1, derived from liver microsomes. INU-101 can enhance insulin sensitivity and lower the fasting blood glucose level. INU-101 can be used for the research of metabolic disease, such as diabetes. | |||||||||||||||||||||
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Keywords
