151503-28-5
Chemical Structure
DMTr-dH2U-amidite
- CAS No.: 151503-28-5
- Formula:C39H47N4O7P
- Molecular Weight:714.79
IUPAC Name: (2R,3S,5R)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-5-(4-oxopyrimidin-1(4H)-yl)tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite
InChIKey: KMZDUEOOUPMTJZ-CWDWRSLKSA-N
SMILES: CC(C)N(C(C)C)P(O[C@H]1C[C@H](N(C=N2)C=CC2=O)O[C@@H]1COC(C3=CC=CC=C3)(C4=CC=C(OC)C=C4)C5=CC=C(OC)C=C5)OCCC#N
Biological Activity: DMTr-dH2U-amidite is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
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DMTr-dH2U-amidite | DMTr-dH2U-amidite is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc. | |||||||||||||||||||||
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Keywords
