1539276-41-9
Chemical Structure
Plm IV inhibitor-1
- CAS No.: 1539276-41-9
- Formula:C37H51N5O3
- Molecular Weight:613.83
IUPAC Name: N1-((2S,3R)-3-hydroxy-1-phenyl-4-((2-(pyridin-2-yl)propan-2-yl)amino)butan-2-yl)-5-(piperidin-1-yl)-N3,N3-dipropylisophthalamide
InChIKey: CSWMOEBFXLXGOK-JHOUSYSJSA-N
SMILES: CCCN(CCC)C(C1=CC(C(N[C@H]([C@H](O)CNC(C)(C2=CC=CC=N2)C)CC3=CC=CC=C3)=O)=CC(N4CCCCC4)=C1)=O
Biological Activity: Plm IV inhibitor-1 (compound 6) is a potent plasmepsin IV (Plm IV) inhibitor with IC50s of 4.1, 0.80, 0.25, 0.35 µM for Plm I, Plm II, Plm IV, Cat D, respectively[1].
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Plm IV inhibitor-1 | Plm IV inhibitor-1 (compound 6) is a potent plasmepsin IV (Plm IV) inhibitor with IC50s of 4.1, 0.80, 0.25, 0.35 µM for Plm I, Plm II, Plm IV, Cat D, respectively. | |||||||||||||||||||||
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Keywords