154788-16-6
Chemical Structure
PNU-145156E
Synonym(s): FCE26644
- CAS No.: 154788-16-6
- Formula:C45H36N10Na4O17S4
- Molecular Weight:1209.04
IUPAC Name: sodium 7,7'-((4,4'-((4,4'-(carbonylbis(azanediyl))bis(1-methyl-1H-pyrrole-4,2-diyl-2-carbonyl))bis(azanediyl))bis(1-methyl-1H-pyrrole-4,2-diyl-2-carbonyl))bis(azanediyl))bis(naphthalene-1,3-disulfonate)
InChIKey: XUWLTCQVQARIFB-UHFFFAOYSA-J
SMILES: O=C(NC1=CN(C)C(C(NC2=CN(C)C(C(NC3=CC4=C(S(=O)(O[Na])=O)C=C(S(=O)(O[Na])=O)C=C4C=C3)=O)=C2)=O)=C1)NC5=CN(C)C(C(NC6=CN(C)C(C(NC7=CC8=C(S(=O)(O[Na])=O)C=C(S(=O)(O[Na])=O)C=C8C=C7)=O)=C6)=O)=C5
Biological Activity: PNU-145156E (FCE26644) is an angiogenesis inhibitor with anti-tumor activity. PNU-145156E inhibits the binding of bFGF to its receptor and inhibits bFGF-induced endothelial cell proliferation and motility[1].
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PNU-145156E | PNU-145156E (FCE26644) is an angiogenesis inhibitor with anti-tumor activity. PNU-145156E inhibits the binding of bFGF to its receptor and inhibits bFGF-induced endothelial cell proliferation and motility. | |||||||||||||||||||||
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Keywords