1565822-28-7
Chemical Structure
FV-162
- CAS No.: 1565822-28-7
- Formula:C25H28F4N4O7S
- Molecular Weight:604.57
IUPAC Name: N-((S)-3-(difluoromethoxy)-1-(((S)-3-(difluoromethoxy)-1-(((S)-1-((R)-2-methyloxiran-2-yl)-1-oxo-3-phenylpropan-2-yl)amino)-1-oxopropan-2-yl)amino)-1-oxopropan-2-yl)-2-methylthiazole-5-carboxamide
InChIKey: HCDMHOLIZBPLBM-RRNUEHDVSA-N
SMILES: O=C(C1=CN=C(C)S1)N[C@@H](COC(F)F)C(N[C@@H](COC(F)F)C(N[C@@H](CC2=CC=CC=C2)C([C@]3(CO3)C)=O)=O)=O
Biological Activity: FV-162 is a potent, orally active and irreversible proteasome inhibitor. FV-162 exhibits cytotoxic to human myeloma cell lines and primary myeloma cells. FV-162 inhibits tumor growth in a myeloma xenograft mouse model. FV-162 can be used for myeloma research[1].
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FV-162 | FV-162 is a potent, orally active and irreversible proteasome inhibitor. FV-162 exhibits cytotoxic to human myeloma cell lines and primary myeloma cells. FV-162 inhibits tumor growth in a myeloma xenograft mouse model. FV-162 can be used for myeloma research. | |||||||||||||||||||||
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Keywords
