157212-55-0
157212-55-0
Chemical Structure
Bosentan hydrate
- CAS No.: 157212-55-0
- Formula:C27H31N5O7S
- Molecular Weight:569.63
IUPAC Name: 4-(tert-butyl)-N-(6-(2-hydroxyethoxy)-5-(2-methoxyphenoxy)-[2,2'-bipyrimidin]-4-yl)benzenesulfonamide hydrate
InChIKey: SXTRWVVIEPWAKM-UHFFFAOYSA-N
SMILES: O=S(NC1=NC(C2=NC=CC=N2)=NC(OCCO)=C1OC3=CC=CC=C3OC)(C4=CC=C(C(C)(C)C)C=C4)=O.O
Biological Activity: Bosentan hydrate is a competitive and dual antagonist of endothelin-1 (ET) for the ETA and ETB receptors with Ki of 4.7 nM and 95 nM in human SMC, respectively.
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Bosentan hydrate | 99.93% | Bosentan hydrate is a competitive and dual antagonist of endothelin-1 (ET) for the ETA and ETB receptors with Ki of 4.7 nM and 95 nM in human SMC, respectively. | ||||||||||||||||||||
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Bosentan hydrate (Standard) | ≥98% | Bosentan (hydrate) (Standard) is the analytical standard of Bosentan (hydrate). This product is intended for research and analytical applications. Bosentan hydrate is a competitive and dual antagonist of endothelin-1 (ET) for the ETA and ETB receptors with Ki of 4.7 nM and 95 nM in human SMC, respectively. | ||||||||||||||||||||
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