1579978-17-8
Chemical Structure
RAS activator compound 1
- CAS No.: 1579978-17-8
- Formula:C25H28ClN5O
- Molecular Weight:449.98
IUPAC Name: (S)-2-amino-N-(1-((5-chloro-1H-indol-3-yl)methyl)piperidin-4-yl)-3-(1H-indol-3-yl)propanamide
InChIKey: LMAYILTVNBZXSW-QFIPXVFZSA-N
SMILES: ClC1=CC=C2C(C(CN3CCC(CC3)NC([C@@H](N)CC4=CNC5=CC=CC=C45)=O)=CN2)=C1
Biological Activity: RAS activator compound 1 (Compound 7c) is a RAS activator targeting the guanine nucleotide exchange factor (GEF) son of sevenless homologue 1 (SOS1). RAS activator compound 1 can activate the nucleotide exchange process and increase levels of active RAS-GTP in HeLa cells. RAS activator compound 1 can be used for research of RAS-driven tumor[1].
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RAS activator compound 1 | 98.90% | RAS activator compound 1 (Compound 7c) is a RAS activator targeting the guanine nucleotide exchange factor (GEF) son of sevenless homologue 1 (SOS1). RAS activator compound 1 can activate the nucleotide exchange process and increase levels of active RAS-GTP in HeLa cells. RAS activator compound 1 can be used for research of RAS-driven tumor. | ||||||||||||||||||||
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Keywords
