1584732-36-4
Chemical Structure
AM-6761
- CAS No.: 1584732-36-4
- Formula:C33H37Cl2FN2O5S2
- Molecular Weight:695.69
IUPAC Name: 2-(2-(((3R,5R,6S)-1-((S)-2-(tert-butylsulfonyl)-1-cyclopropylethyl)-6-(4-chloro-3-fluorophenyl)-5-(3-chlorophenyl)-3-methyl-2-oxopiperidin-3-yl)methyl)thiazol-5-yl)acetic acid
InChIKey: HNLHOKSDTBAERS-CWIPYCOQSA-N
SMILES: O=C(O)CC1=CN=C(C[C@]2(C)C(N([C@@H](C3CC3)CS(=O)(C(C)(C)C)=O)[C@H](C4=CC=C(Cl)C(F)=C4)[C@@H](C5=CC=CC(Cl)=C5)C2)=O)S1
Biological Activity: AM-6761 is a potent MDM2 inhibitor with an IC50 of 0.1 nM.
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AM-6761 | AM-6761 is a potent MDM2 inhibitor with an IC50 of 0.1 nM. | |||||||||||||||||||||
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Keywords