1597403-47-8
1597403-47-8
Chemical Structure
ISRIB (trans-isomer)
- CAS No.: 1597403-47-8
- Formula:C22H24Cl2N2O4
- Molecular Weight:451.34
IUPAC Name: N,N'-((1r,4r)-cyclohexane-1,4-diyl)bis(2-(4-chlorophenoxy)acetamide)
InChIKey: HJGMCDHQPXTGAV-IYARVYRRSA-N
SMILES: O=C(N[C@H]1CC[C@H](NC(COC2=CC=C(Cl)C=C2)=O)CC1)COC3=CC=C(Cl)C=C3
Biological Activity: ISRIB (trans-isomer) is a potent inhibitor of PERK with an IC50 of 5 nM. ISRIB potently reverses the effects of eIF2α phosphorylation (IC50=5 nM).
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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ISRIB (trans-isomer) | 99.49% | ISRIB (trans-isomer) is a potent inhibitor of PERK with an IC50 of 5 nM. ISRIB potently reverses the effects of eIF2α phosphorylation (IC50=5 nM). | ||||||||||||||||||||
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Keywords
