160037-48-9
160037-48-9
Chemical Structure
Janus-DOTA
- CAS No.: 160037-48-9
- Formula:C54H80N10O18S2
- Molecular Weight:1221.40
InChIKey: DKONDHNAERRXQL-UHFFFAOYSA-N
SMILES: O=C(CN1CCN(CCN(C(CN(CC1)CC(O)=O)CC2=CC=C(NC(CSCCCCSCC(NC3=CC=C(CC4N(CCN(CCN(CCN(C4)CC(O)=O)CC(O)=O)CC(O)=O)CC(O)=O)C=C3)=O)=O)C=C2)CC(O)=O)CC(O)=O)O
Biological Activity: Janus-DOTA is a bivalent hapten, can be used for drug delivery[1].
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Janus-DOTA | Janus-DOTA is a bivalent hapten, can be used for drug delivery. | |||||||||||||||||||||
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References
- [1]. Goodwin DA, et al. Pharmacokinetics of pretargeted monoclonal antibody 2D12.5 and 88Y-Janus-2-(p-nitrobenzyl)-1,4,7,10-tetraazacyclododecanetetraacetic acid (DOTA) in BALB/c mice with KHJJ mouse adenocarcinoma: a model for 90Y radioimmunotherapy. Cancer Res. 1994 Nov 15;54(22):5937-46. [Content Brief]
Keywords
