160203-74-7
160203-74-7
Chemical Structure
5’-O-Acetyl-2’,3’-dideoxy-2’,3’-didehydro-5-fluoro-uridine
- CAS. Nr.: 160203-74-7
- Formula:C11H11FN2O5
- Molecular Weight:270.21
IUPAC Name: ((2S,5R)-5-(5-fluoro-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-2,5-dihydrofuran-2-yl)methyl acetate
InChIKey: KMQULMAOYWPJKG-IONNQARKSA-N
SMILES: FC1=CN(C(NC1=O)=O)[C@@H]2O[C@H](COC(C)=O)C=C2
Biological Activity: 5’-O-Acetyl-2’,3’-dideoxy-2’,3’-didehydro-5-fluoro-uridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
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5’-O-Acetyl-2’,3’-dideoxy-2’,3’-didehydro-5-fluoro-uridine | 5’-O-Acetyl-2’,3’-dideoxy-2’,3’-didehydro-5-fluoro-uridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc. | |||||||||||||||||||||
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References
