1612192-00-3
1612192-00-3
Chemical Structure
2-Chloro-6-(furan-2-yl) purine-beta-D-(3’-deoxy-3’-fluoro)-riboside
- CAS No.: 1612192-00-3
- Formula:C14H12ClFN4O4
- Molecular Weight:354.72
IUPAC Name: (2R,3S,4S,5R)-2-(2-chloro-6-(furan-2-yl)-9H-purin-9-yl)-4-fluoro-5-(hydroxymethyl)tetrahydrofuran-3-ol
InChIKey: FUAYUQXTQUOELP-KMEHANEDSA-N
SMILES: ClC(N=C1C2=CC=CO2)=NC3=C1N=CN3[C@@H]4O[C@H](CO)[C@@H](F)[C@H]4O
Biological Activity: 2-Chloro-6-(furan-2-yl) purine-beta-D-(3’-deoxy-3’-fluoro)-riboside is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
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2-Chloro-6-(furan-2-yl) purine-beta-D-(3’-deoxy-3’-fluoro)-riboside | 2-Chloro-6-(furan-2-yl) purine-beta-D-(3’-deoxy-3’-fluoro)-riboside is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc. | |||||||||||||||||||||
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