161923-50-8
161923-50-8
Chemical Structure
6-Chloro-2-hydroxy-9-(2',3',5'-tri-O-acetyl-β-D-ribofuranosyl)purine
- CAS No.: 161923-50-8
- Formula:C16H17ClN4O8
- Molecular Weight:428.78
IUPAC Name: (2R,3R,4R,5R)-2-(acetoxymethyl)-5-(6-chloro-2-hydroxy-9H-purin-9-yl)tetrahydrofuran-3,4-diyl diacetate
InChIKey: UDPLUTIBYLKPII-SDBHATRESA-N
SMILES: ClC1=NC(O)=NC2=C1N=CN2[C@@H]3O[C@H](COC(C)=O)[C@@H](OC(C)=O)[C@H]3OC(C)=O
Biological Activity: 6-Chloro-2-hydroxy-9-(2',3',5'-tri-O-acetyl-β-D-ribofuranosyl)purine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
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6-Chloro-2-hydroxy-9-(2',3',5'-tri-O-acetyl-β-D-ribofuranosyl)purine | 6-Chloro-2-hydroxy-9-(2',3',5'-tri-O-acetyl-β-D-ribofuranosyl)purine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc. | |||||||||||||||||||||
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