1621585-17-8
Chemical Structure
PF-06649283
- CAS No.: 1621585-17-8
- Formula:C18H19F2N3O2S
- Molecular Weight:379.42
IUPAC Name: (4R,4aR,6R,8aS)-8a-(2,4-difluorophenyl)-4-methyl-6-(3-methylisoxazol-5-yl)-4,4a,5,6,8,8a-hexahydropyrano[3,4-d][1,3]thiazin-2-amine
InChIKey: HVEVDFRWOQHAPJ-CKMNQQOVSA-N
SMILES: [H][C@]12[C@@](C3=CC=C(C=C3F)F)(N=C(S[C@@H]2C)N)CO[C@H](C1)C4=CC(C)=NO4
Biological Activity: PF-06649283 is a drug with potential intracellular activity. The effects of PF-06649283 may be affected by factors such as cellular metabolism, protein-protein interactions, post-translational modifications, and asymmetric intracellular localization. The potency of PF-06649283 at the cellular level may show different activity compared to the recombinant enzyme, and this difference needs to be considered in the drug discovery process. Increased intracellular potency of PF-06649283 may be critical for the development of this drug as a probe or drug[1].
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PF-06649283 | PF-06649283 is a drug with potential intracellular activity. The effects of PF-06649283 may be affected by factors such as cellular metabolism, protein-protein interactions, post-translational modifications, and asymmetric intracellular localization. The potency of PF-06649283 at the cellular level may show different activity compared to the recombinant enzyme, and this difference needs to be considered in the drug discovery process. Increased intracellular potency of PF-06649283 may be critical for the development of this drug as a probe or drug. | |||||||||||||||||||||
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Keywords
