1622180-31-7
Chemical Structure
BMS-986104
- CAS No.: 1622180-31-7
- Formula:C22H35NO
- Molecular Weight:329.52
IUPAC Name: ((1R,3S)-1-amino-3-((R)-6-hexyl-5,6,7,8-tetrahydronaphthalen-2-yl)cyclopentyl)methanol
InChIKey: BPMMYKAHRIEVDH-VOQZNFBZSA-N
SMILES: OC[C@@]1(C[C@@](CC1)([H])C2=CC=C(C[C@@H](CC3)CCCCCC)C3=C2)N
Biological Activity: BMS-986104 is a potent and selective S1P1 receptor modulator. BMS-986104 is effective in a mouse EAE model, which is comparable to FTY720. Mechanistically, BMS-986104 exhibites excellent remyelinating effects on lysophosphatidylcholine (LPC)-induced demyelination in a three-dimensional brain cell culture assay.
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BMS-986104 | BMS-986104 is a potent and selective S1P1 receptor modulator. BMS-986104 is effective in a mouse EAE model, which is comparable to FTY720. Mechanistically, BMS-986104 exhibites excellent remyelinating effects on lysophosphatidylcholine (LPC)-induced demyelination in a three-dimensional brain cell culture assay. | |||||||||||||||||||||
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Keywords
