1630804-24-8
Chemical Structure
IQS-019
- CAS 番号: 1630804-24-8
- Formula:C25H25Cl2N7O
- Molecular Weight:510.42
IUPAC Name: 4-amino-6-(2,6-dichlorophenyl)-8-methyl-2-((4-(4-methylpiperazin-1-yl)phenyl)amino)pyrido[2,3-d]pyrimidin-7(8H)-one
InChIKey: ZAPKBDATQCZIDX-UHFFFAOYSA-N
SMILES: O=C1C(C2=C(Cl)C=CC=C2Cl)=CC3=C(N)N=C(NC4=CC=C(N5CCN(C)CC5)C=C4)N=C3N1C
Biological Activity: IQS-019 is a B cell receptor (BCR) kinase inhibitor. IQS-019 can inhibit the de-phosphorylation of constitutive and IgM-activated Syk, Lyn, and Btk. IQS-019 can inhibit cell proliferation, migration and induce apoptosis. IQS-019 exhibits antitumor activity and can be used for the research of cancer, such as B cell lymphoma[1].
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IQS-019 | IQS-019 is a B cell receptor (BCR) kinase inhibitor. IQS-019 can inhibit the de-phosphorylation of constitutive and IgM-activated Syk, Lyn, and Btk. IQS-019 can inhibit cell proliferation, migration and induce apoptosis. IQS-019 exhibits antitumor activity and can be used for the research of cancer, such as B cell lymphoma. | |||||||||||||||||||||
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Keywords
