1631170-04-1
1631170-04-1
Chemical Structure
HCV-IN-49
- CAS No.: 1631170-04-1
- Formula:C22H27D3N3O10P
- Molecular Weight:530.48
SMILES: O=C(N1)N([C@@H]2O[C@H](C([2H])([2H])O[P@@](N[C@@H](C)C(OC(C)C)=O)(OC3=CC=CC=C3)=O)[C@@H](O)[C@@]2(C)O)C=C([2H])C1=O
Biological Activity: HCV-IN-49, a phosphoramidate ester derivative, is a HCV protease inhibitor[1].
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HCV-IN-49 | HCV-IN-49, a phosphoramidate ester derivative, is a HCV protease inhibitor. | |||||||||||||||||||||
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N-[[P(S)]-2'-C-Methyl-P-phenyl-5'-uridylyl]-L-Ala-1-methylethyl ester | N-[[P (S)]-2'-C-Methyl-P-phenyl-5'-uridylyl]-L-Ala-1-methylethyl ester is a 5'(S)-C-methyl phosphoramidate prodrug of 2',5'-C-dimethyluridine, as well as a HCV inhibitor. N-[[P (S)]-2'-C-Methyl-P-phenyl-5'-uridylyl]-L-Ala-1-methylethyl ester induces anti-HCV activity in HCV genotype 1b replicons with extremely low cytotoxicity. N-[[P (S)]-2'-C-Methyl-P-phenyl-5'-uridylyl]-L-Ala-1-methylethyl ester can be used in studies related to HCV infection. | |||||||||||||||||||||
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References
